In a case of art imitating life, Lois Cerullo is putting Port Charles in her rearview mirror — because her portrayer is saying goodbye to Hollywood.

Longtime General Hospital star Rena Sofer announced on social media this week that she and husband Sanford Bookstaver are leaving Los Angeles, where the ABC soap is filmed, after almost 35 years.

“Yes I’m getting emotional,” Sofer wrote on Instagram. “I met and had my children in LA met the man of my dreams and created an incredible life there. I had amazing success in the Biz and made all my lifelong friends who I will miss desperately. … Thank you LA for being you. And now on to quieter and calmer times. Leave it to a leaf blower to finish this post, there is nothing more la!! Now we are off … with our 5 dogs in the back to our new life!!!”

According to Daytime Confidential, Lois is being written out of the show with the door being kept open for her return, should Sofer ever decide to pay Hollywood a visit. So at least we know she’s not being killed off! An airdate for Sofer’s final episode as Lois is not yet known.

Sofer has portrayed Lois on and off since 1993, winning a Daytime Emmy Award for her performance in 1995. Her other major daytime role came via The Bold and the Beautiful, on which she played Quinn Fuller from 2013 to 2022. Sofer’s primetime credits include memorable roles on 24, Melrose Place, Once Upon a Time and NCIS, among many others.

TVLine has reached out to ABC for additional information. Will you miss Lois on General Hospital? Drop a comment with your thoughts on Sofer’s exit below.